Friday, March 25, 2016

Most Common Diseases of elder: Respiratory Pleural disease: Pleural effusion Treatment caused by systemic diseases

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

                                          Respiratory Disease

Respiratory Disease is defined as medical conditions, affecting the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

                   Pleural disease: Pleural effusion

The pleura is a thin tissue covered by a layer of cells (mesothelial cells) that surrounds the lungs and lines the inside of the chest wall.
Pleural effusion is a condition of collection of fluid within the pleural cavity as a result of heart failure, bleeding (hemothorax), infections, excessive or decreased fluid volume, etc.

                     The Treatment

 Treatments in conventional medicine perspective
Pleural effusions caused by systemic diseases
Despite the low incidence (around 1%) of pleural effusions caused by systemic diseases, more often connective tissue diseases, such as rheumatoid arthritis or systemic lupus erythematosus.
Intra thoracic administration of cisplatin and sodium thiosulfate
In the study to to examine the pharmacokinetics and side effects of CDDP of Twenty-eight patients with malignant pleural effusion received instillation of cisplatin (CDDP) into the pleural cavity Thirteen patients received high-dose CDDP (120 mg/m2-160 mg/m2) in combination with sodium thiosulfate (STS), while 15 others received CDDP alone (80 mg/m2), found that malignant pleural effusion could be effectively treated by the instillation of CDDP 80 mg/m2 into the pleural cavity(104).

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Sources
(104) http://www.ncbi.nlm.nih.gov/pubmed/3196043

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