Monday, May 30, 2016

Most common Diseases Free and Longevity of 50 plus - Organic Soy Part A By Whole Foods SoyBean

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Over the years of research, 4 foods appeared mostly in medical studies in preventing and treating diseases, are Green Tea, Grape seed and skin, Turmeric and Organic Soy(Not for Western Women). All Right Reserved.

IV. Organic Soy
Soy foods, including tofu have been in traditional Chinese diet over thousands of year, according to Chinese literature. The reduced risk of chronic disease in Asian population, including metabolic syndrome such as cardiovascular diseases, obesity and diabetes and lesser menopause symptoms in advanced age, may be aided by eating a lot of soy food accompanied with large portion of vegetables and fruits. Indeed, according to the study, only 10% of women in the East are experience symptoms of menopause in advanced age compared to over 70% of their Western counterparts.
According to Dr. Mark Messina, Ph.D., Soy foods contributed from 6.5%8 to 12.8%7 of total protein intake in older adult in Japan.(b)

The approval of cardiovascular benefit of soy by FDA in 1999 accompanied with the discovery of health benefits in clinical studies over past decade, prompted the promotion and advertisement of soy's health benefits in every aspect in Western society. Evidences could be seen by walking through the supermarkets and drug stores. Soy supplements and products such as tofu, soy milk, soy-based infant formula, and meatless “texturized vegetable protein” burgers were widely available. According to the United Soybean Board’s 2004–2005, 25% of Americans consumed soy foods or beverages at least once per week, and 74% viewed soy products as healthy.

Today, the promotion of soy is no longer existed, it may be results of discovery of adverse effects in single ingredient and animal studies, as intake of soy is associated to induce risk of certain mammary cancers and infertility. The publication of the result have drawn many criticisms. According to Thomas Badger, director and senior investigator at the Arkansas Children’s Nutrition Center in Little Rock, these effects are seen only under certain experimental conditions that are not likely to occur in humans—and therein lies the crux of the debate(a).Equol (4',7-isoflavandiol), an isoflavandiol metabolized from daidzein may be the causes, as 90% of Eastern population are equol producers but only 30% in the West.
The explanation of the positive effect of soy isoflavones in reduced risk of mammary cancers by University of Goettingen may be interesting, as researchers said" Most importantly, there is dispute as to whether isoflavones derived from soyor red clover have negative, positive or any effect at all on the mammary gland or endometrium. It is beyond any doubt that soy products may have cancerpreventing properties in a variety of organs including the mammary gland. However, these properties may only be exerted if the developing organ was under the influence of isoflavones during childhood and puberty".

Soybean is genus Glycine, the family Fabaceae, one of the legumes that contains twice as much protein per acre as any other major vegetable or grain crop, native to Southeast Asia. Now, it is grown worldwide with suitable climate for commercial profit and a a healthy foods.

Nutrients
1. Carbohydrates
2. Dietary fiber
3. Fat
4. Protein
5. Essential amino acid
6. Vitamin A
7. Vitamin B6
8. Vitamin B12
9. Vitamin C
10. Vitamin K
11. Calcium
12. Iron
13. Magnesium
14. Phosphorus
15. Potassium
16. Sodium
17. Zinc
18. Etc.
Phytochemicals
1. Isoflavones
2. Genistein
3. Saponins
4. Beta-sitosterol
5. Daidzein


II. Health Benefits
A. Health Benefits according to studies

1. Insulin sensitive
Soybean helps to normalize plasma glucose and insulin homeostasis, according to "Increased insulin sensitivity and changes in the expression profile of key insulin regulatory genes and beta cell transcription factors in diabetic KKAy-mice after feeding with a soy bean protein rich diet high in isoflavone content" by Nordentoft I, Jeppesen PB, Hong J, Abudula R, Hermansen K.(a)

2. Cardiovascular diseases
Soy protein reduces reduces the levels of serum lipoprotein, decrease in low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), LDL-C/high-density lipoprotein cholesterol (HDL-C), triacylglycerol/HDL-C and TC/HDL-Cpostmenopausal women are at risk of cardiovascular disease, according to "Effects of soy bean on serum paraoxonase 1 activity and lipoproteins in hyperlipidemic postmenopausal women" by Shidfar F, Ehramphosh E, Heydari I, Haghighi L, Hosseini S, Shidfar S.(b)

3. Adipogenesis and Adipolysis
Germinated soy bean protein hydrolysates had an effect on inhibition of lipid storage in adypocites and increasing lipolysis, according to "Effect of Germinated Soybean Protein Hydrolysates on Adipogenesis and Adipolysis in 3T3-L1 Cells" by González-Espinosa de Los Monteros LA, Ramón-Gallegos E, Torres-Torres N, Mora-Escobedo R.(c)

4. Antioxidant effects
Extract from Virginia-grown soybean seeds had exerted its antioxidant effect when compared for their total phenolic contents (TPC), oxygen radical absorbance capacity (ORAC), and 2,2-diphenyl-1-picrylhydrazyl radical (DPPH(*)) scavenging activities, according to "Comparison of different strategies for soybeanantioxidant extraction" by Chung H, Ji X, Canning C, Sun S, Zhou K.(d)

5. Diabetes and hypertension
Soybean phenolic-rich extracts has exerted the inhibitory activities of phenolic-rich extracts from soybean on α-amylase, α-glucosidase and angiotensin I converting enzyme (ACE) activities in vitro, according to "Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro" by Ademiluyi AO, Oboh G.(e)

6. Etc.

B. Health Benefits according to the concentration
1. Molybdenum
Molybdenum cofactor is vital for human enzymes, including xanthine oxidase, sulfite oxidase, and aldehyde oxidase, Deficiency may cause Prenatal brain disruption, according to the study of "Prenatal brain disruption in molybdenum cofactor deficiency" by Carmi-Nawi N, Malinger G, Mandel H, Ichida K, Lerman-Sagie T, Lev D.(1)

2. Tryptophan
Tryptophan beside is the precosur of serotonin as it is famous in inducing sleep if it taken in high dose,according to the study of "Improving the quality of infant sleep through the inclusion at supper of cereals enriched with tryptophan, adenosine-5'-phosphate, and uridine-5'-phosphate" by Cubero J, Chanclón B, Sánchez S, Rivero M, Rodríguez AB, Barriga C.(2), it also enhances the neural responses cayused by depression, according to the study of "The effects of tryptophan depletion on neural responses to emotional words in remitted depression" by Roiser JP, Levy J, Fromm SJ, Nugent AC, Talagala SL, Hasler G, Henn FA, Sahakian BJ, Drevets WC.(3)

3. Mangannese
It is one of important trace in preventing osteroposis, according to the study of "[Study of estrogen deficiency impact on manganese levels in teeth and mandible of rats after ovariectomy]. [Article in Polish]" by Rahnama M, Błoniarz J, Zareba S, Swiatkowski W.(4)and regulating blood sugar level, according to the study of "[An inadequate intake of manganese may favour insulin resistance in girls]. [Article in Spanish]" by Rodríguez-Rodríguez E, Bermejo LM, López-Sobaler AM, Ortega RM.(5)

4. Protein
Protein in Soybean is not only beneficial to the cardiovascular diseases, according to the study of "Soy protein, isoflavones, and cardiovascular health: an American Heart Association Science Advisory for professionals from the Nutrition Committee" by Sacks FM, Lichtenstein A, Van Horn L, Harris W, Kris-Etherton P, Winston M; American Heart Association Nutrition Committee(6), but also plays an important role in treating diabetes, according to "Effects of soy protein and isoflavones on glycemic control and insulin sensitivity: a 6-mo double-blind, randomized, placebo-controlled trial in postmenopausal Chinese women with prediabetes or untreated early diabetes" by Liu ZM, Chen YM, Ho SC, Ho YP, Woo J.(7)

5. Etc.

C. Other health benefits
1. Aspartic acid
Aspartic acid not only helps to protect the body from drug toxicity and radiation, it also plays an essential role for the brain in information transmitting across the synapse, thus enhancing the learning and memory mechanism, according to the study of "Disinhibition-Mediated LTP in the Hippocampus is Synapse Specific" byOrmond J, Woodin MA., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21954377

2. Histidine
Histidine plays an important role in promoting white and red blood cells, thus increasing the immune system in fight against forming of free radical and reducing the risk anemia., according to the study of "The role of histidine in the anemia of folate deficiency" by Cooperman JM, Lopez R., posted in PubMed(http://www.ncbi.nlm.nih.gov/pubmed/12486209), researchers concluded that concluded that folate deficiency causes histidine depletion through increased urinary excretion of this amino acid. Feeding histidine replenishes tissue levels ofhistidine, resulting in hemoglobin regeneration. Folic acid administration results in return of histidine to normal urinary levels. Thus, a combination of folic acidhistidine would be beneficial for folate deficient individuals.

3. Serine
As an amino acid, serine in soybean not only helps to maintain proper muscle build up by synthesizing fatty acids and proteins, it also is important for brain in to transport information between themselves and cells in other parts of the body, according to the study of "Transport systems of serine at the brain barriers and inbrain parenchymal cells" by Kasai Y, Tachikawa M, Hirose S, Akanuma S, Hosoya K., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/21592122)

4. Alanine
Alanine not only is essential in production of energy in glucose synthesis (according to the study ofGlucose and insulin effects on the novo amino acidsynthesis in young men: studies with stable isotope labeled alanine, glycine, leucine, and lysine" by Robert JJ, Bier DM, Zhao XH, Matthews DE, Young VR., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/6815417) it also enhances the immune system in production of anti bodies., according to the study of "Theimmune response of tetraparental mice to two synthetic amino acid polymers: "high-conjugation" 2,4 dinitrophenyl-glutamic acid57-lysine38-alanine5 (DNP-GLA5) and glutamic acid60 alanine30 tyrosine10 (GAT10)" by Warner CM, Fitzmaurice M,Maurer PH, Merryman CF, Schmerr MJ., posted in The Journey of Immunology (http://www.jimmunol.org/content/111/6/1887)

5. Isoleucine
Another animo acid helps to maintain the body tissues and store glycogen in muscles thereby reducing the risk of muscle breaking down during physical activity., according to the study of "Isoleucine, a potent plasma glucose-lowering amino acid, stimulates glucose uptake in C2C12 myotubes" by Doi M, Yamaoka I, Fukunaga T, Nakayama M., posted in PubMed (http://www.ncbi.nlm.nih.gov/pubmed/14651987), researchers that isoleucinestimulates the insulin-independent glucose uptake in skeletal muscle cells, which may contribute to the plasma glucose-lowering effect of isoleucine in normal rats.

6. Etc.

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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/18522411
(b) http://www.ncbi.nlm.nih.gov/pubmed/18608549
(c) http://www.ncbi.nlm.nih.gov/pubmed?term=Effect%20of%20Germinated%20Soybean%20Protein%20Hydrolysates%20on%20Adipogenesis%20and%20Adipolysis%20in%203T3-L1%20Cells
(d) http://www.ncbi.nlm.nih.gov/pubmed/20302378
(e) http://www.ncbi.nlm.nih.gov/pubmed/22005499

(1) http://www.ncbi.nlm.nih.gov/pubmed/21285035
(2) http://www.ncbi.nlm.nih.gov/pubmed/19925721
(3) http://www.ncbi.nlm.nih.gov/pubmed/19539268
(4) http://www.ncbi.nlm.nih.gov/pubmed/12870295
(5) http://www.ncbi.nlm.nih.gov/pubmed/22072339
(6) http://www.ncbi.nlm.nih.gov/pubmed/16418439
(7) http://www.ncbi.nlm.nih.gov/pubmed/20335543

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