Tuesday, June 7, 2016

Most Common Diseases of elder: Respiratory Disease: Benign lung tumors - The Antioxidants

Kyle J. Norton(Scholar and Master of Nutrients)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Respiratory Disease is defined as medical conditions which affect the breathing organ and tissues including Inflammatory lung disease, Obstructive lung diseases, Restrictive lung diseases, Respiratory tract infections, trachea, bronchi, bronchioles, alveoli, the nerves and muscles breathing , etc,.

Benign lung tumors, growth from many different structures in the lung, is defined as a conditions of abnormal cell growth with no tendency of spreading or masses that push normal cells out of the way rather than invading surrounding tissue restricted to a limited area in the lung. Approximately one out of 500 chest radiographs shows the incidental finding of a solitary pulmonary nodule and almost one half of these pulmonary lesions are caused by a tumor. Unfortunately, only 2% to 5% of alllung tumors are of benign origin, e. g. lipoma, fibroma, hamartoma, and chondroma, and the majority are malignant, most commonly primarylung cancer followed by metastases of extrapulmonary primary carcinomas. According to the study by Universitätsklinik für Pneumologie(a).

Antioxidants to prevent benign lung tumors

In the study to determine whether vitamins, minerals and other potential agents, alone or in combination, reduce incidence and mortality from lung cancer in healthy people, showed that
1. Zinc and copper
Zinc, copper and selenium are important cofactors for several enzymes that play a role in maintaining DNA integrity. However, limited epidemiologic research on these dietary trace metals and lung cancer risk is available. According to the study by,dietary zinc and copper intakes are associated with reduced risk of lung cancer. Given the known limitations of case-control studies, these findings must be interpreted with caution and warrant further investigation(26).

2. Antioxidants vitamin C and vitamin E
In the study to evaluate the evidence of the supplements vitamin C and vitamin E for treatment and prevention of cancer, identified only 3 studies that reported statistically significant beneficial results: vitamin C (in combination with BCG) was found to be beneficial in a single trial of bladder cancer and vitamin E (in combination with omega-3 fatty acid) increased survival in patients with advancedcancer. In the ATBC trial, in analyses of 6 individual cancers, the prevention of prostate cancer in subjects treated with alpha-tocopherol was statistically significant (RR=0.64, 95% CI: 0.44, 0.94)(27).

3. Selenium
In a systematic review of selenium for lung cancers, and assessed potential interactions with conventional therapies, found that Selenium may be effective forlung cancer prevention among individuals with lower selenium status, but at present should not be used as a general strategy for lung cancer prevention. Although promising, more evidence on the ability of selenium to reduce cisplatin and radiation therapy toxicity is required to ensure that therapeutic efficacy is maintained before any broad clinical recommendations can be made in this context(28).

4. Etc.

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Sources
(a) http://www.ncbi.nlm.nih.gov/pubmed/22753285
(26) http://www.ncbi.nlm.nih.gov/pubmed/17131334
(27) http://www.ncbi.nlm.nih.gov/pubmed/16808775
(28) http://www.ncbi.nlm.nih.gov/pubmed/22073154

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