Sunday, November 12, 2017

Hormone Norepinephrine: Norepinephrine facilitates inhibitory transmission in substantia gelatinosa of adult rat spinal cord

Kyle J. Norton(Scholar and Master of Nutrients, all right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.                     

                        Hormone Catecholamines


Catecholamines, derived from the amino acid tyrosine, produced by the adrenal glands, which are found on top of the kidneys. are epinephrine (adrenaline), norepinephrine (noradrenaline) and dopamine. The hormone are released into the blood during times of physical or emotional stress.

     Hormone Norepinephrine: Norepinephrine facilitates inhibitory transmission in substantia gelatinosa of adult rat spinal cord 



The activation of descending norepinephrine-containing fibers from the brain stem inhibits nociceptive transmission at the spinal level.In the study to evaluate the descending noradrenergic pathways exert the analgesic effect, found that norepinephrine enhances inhibitory synaptic transmission in the substantia gelatinosa through activation of presynaptic alpha1 receptors, thus providing a mechanism underlying the clinical use of alpha1 agonists with local anesthetics in spinal anesthesia(10).


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Sources
(10) http://www.ncbi.nlm.nih.gov/pubmed/10691235

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